Sensitivity and Treatment of Infectious Mastitis Pathogens in Cows to Antibiotics

https://doi.org/10.51699/ajbns.v3i3.2190
Cattle Infectious Mastitis Strain Antibiotics Disease Fibrosis Staphylococci Streptococci Enterococci Escherichia Coli Proteus Pseudomonas Penicillin Streptomycin Sulfadiazine Chloramphenicol Tetracycline Enrofloxacin Kanamycin Monomycin Polymyxin Erythromycin Oleandomycin Tylosin Pathogen Catarrhal Subclinical Purulent Mastitis

Authors

  • Amirov Abdumumin Ikromovich
    [email protected]
    Associate Professor, Department of Veterinary Medicine, Tashkent State Agrarian University, University str., 2, Tashkent province, 100140, Uzbekistan
  • Abdurasulov Shavkat Abdurasul og‘li Tashkent State Agrarian University, Department of Veterinary Medicine, Doctor of Veterinary Sciences, Associate Professor, University str., 2, Tashkent province, 100140, Uzbekistan
  • Abdusattorov Abdusalom Professor, Department of Infectious and Parasitic Animal Diseases, Tashkent Branch of Samarkand Institute of Veterinary Medicine, Animal Husbandry and Biotechnology
  • Norbutaeva Sabrina Bakhrom qizi Tashkent State Agrarian University, Student of the Zooengineering Faculty, Veterinary Sanitary Examination program, University str., 2, Tashkent province, 100140, Uzbekistan
Vol. 3 No. 3 (2026): American Journal of Biology and Natural Sciences
Articles
March 28, 2026

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The article presents data on the sensitivity of pathogens (staphylococci, streptococci, enterococci, Escherichia, Proteus, and Pseudomonas) to antibacterial drugs prior to the treatment of cows suffering from infectious mastitis. The sensitivity of these microorganisms to penicillin, streptomycin, sulfadiazine, chloramphenicol, tetracycline, enrofloxacin, kanamycin, monomycin, polymyxin, erythromycin, oleandomycin, tylosin, as well as anti-mastitis preparations Mastisan and Mastisept, was determined by the indicator disk method. When the diameter of the growth inhibition zone of the culture was 15–25 mm, sensitivity was evaluated as moderate; more than 25 mm as high; and the absence of an inhibition zone indicated resistance of the microorganism to the corresponding antibiotic. The results of sensitivity studies of the above-mentioned staphylococci, streptococci, enterococci, Escherichia, Proteus, and Pseudomonas to antibacterial drugs are presented. It was established that the average overall effectiveness of treatment of serous, catarrhal, fibrinous, purulent, and subclinical mastitis with Mastisan was about 80%. The Mastisept preparation showed an average overall treatment effectiveness of 85% for the indicated forms of mastitis, while in 14% of cows incomplete recovery of milk productivity was observed.