A Stable Lycopene–Micronutrient Matrix for Male Reproductive Nutrition: Formulation Characterization and Human Evidence on Sperm Quality

Oxidative conditions around sperm cells and the availability of several micronutrients are relevant to membrane integrity, motility and morphology. We examined the formulation performance of the BCLC® low-moisture, lycopene-centered multinutrient tablet and reviewed human evidence most directly related to its reproductive-nutrition rationale. The daily two-tablet dose supplies 4.5–5.5 mg lycopene, 9.5–10.5 mg zinc, 28–32 μg selenium, vitamin C 75–85 mg, vitamin E 10–13 mg, folic acid 180–220 μg, vitamin D3, B vitamins, taurine and pumpkin seed extract. After accelerated storage, lycopene retention was 89.6%, the optimized tablet had the lowest appearance color change (ΔE 2.3) among the tested formulations, and lycopene content RSD was 3.8%. Randomized studies of lactolycopene or lycopene at 14–25 mg/day have reported changes in selected sperm-motility, morphology or oxidative-stress endpoints, while the large MOXI multicomponent trial found no broad improvement in semen or pregnancy outcomes. The formulation data define a stable exposure platform for testing discrete semen-quality and redox endpoints with the complete BCLC® matrix.