The Outcomes of Sub Inguinal Varicocelectomy on Seminal Fluid Analysis Parameters in Infertile Patients with Clinically Diagnosed Varicoceles
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Background; a comparison study in seminal fluid parameters (count, motility and morphology) pre and post subinguinal varicocelectomy, in patients with history of primary infertility, normal sperm count and clinically diagnosed varicocele.
Patients and method; in this study one hundred infertile patients had primary infertility (1-7 years), normal sperm density and clinical confirmed varicocele were included. A seminal fluid analysis has been recorded preoperative and sex months post varicocelectomy.
Results; 100 patients included in this study; mean age was 22.43± 7.24.
Mean period of infertility was 2.5 years (ranging from 2-7 years), a significant changing in motility has been noted postoperative in normal sperm count patients.
Conclusion; in patients with primary infertility, varicocele and normal sperm count preoperatively there was significant improvement in sperm motility post varicocelectomy while no postoperative significant improvement in sperm morphology for those patients.
[1] [1] M. Cocuzza, M. A. Cocuzza, F. M. P. Bragais, and A. Agarwal, “The role of varicocele repair in the new era of assisted reproductive technology,” Clinics, vol. 63, no. 3, pp. 395–404, 2008.
[2] [2] A. Agarwal, F. Deepinder, M. Cocuzza, et al., “Efficacy of varicocelectomy in improving semen parameters: New meta-analytical approach,” Urology, vol. 70, no. 3, pp. 532–538, 2007.
[3] [3] C. G. Blumer, A. E. Restelli, P. T. D. Giudice, et al., “Effect of varicocele on sperm function and semen oxidative stress,” BJU Int., vol. 109, no. 2, pp. 259–265, 2012.
[4] [4] A.-F. Abdel-Maguid and I. Othman, “Microsurgical and nonmagnified subinguinal varicocelectomy for infertile men: A comparative study,” Fertil. Steril., vol. 94, no. 7, pp. 2600–2603, 2010.
[5] [5] WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction, 5th ed. Cambridge, U.K.: Cambridge Univ. Press, 2010.
[6] [6] D. A. Paduch and J. Niedzielski, “Repair versus observation in adolescent varicocele: A prospective study,” J. Urol., vol. 158, no. 3, pp. 1128–1132, 1997.
[7] [7] L. Okeke, O. Ikuerowo, I. Chiekwe, B. Etukakpan, O. Shittu, and O. Olapade-Olaopa, “Is varicocelectomy indicated in subfertile men with clinical varicoceles who have asthenospermia or teratospermia and normal sperm density?” Int. J. Urol., vol. 14, no. 8, pp. 729–732, 2007.
[8] [8] A. Mancini, E. Meucci, D. Milardi, et al., “Seminal antioxidant capacity in pre- and postoperative varicocele,” J. Androl., vol. 25, no. 1, pp. 44–49, 2004.
[9] [9] A. Maciejko, P. Kim, T. Jang, R. E. Brannigan, and W. W. Lin, “Isolated teratospermia: Is varicocelectomy indicated?” J. Urol., vol. 173, suppl. 4, p. 369, 2005.
[10] [10] M. Marmar, K. Benoff, L. M. Reijo-Pera, and A. Agarwal, “The pathophysiology of varicoceles in the light of current molecular and genetic information,” Hum. Reprod. Update, vol. 13, no. 3, pp. 271–283, 2007.
[11] [11] S. Fretz and K. Sandlow, “Varicocele: Current concepts in pathophysiology, diagnosis, and treatment,” Urol. Clin. North Am., vol. 29, no. 4, pp. 921–937, 2002.
[12] [12] R. M. Sharlip et al., “Best practice policies for male infertility,” Fertil. Steril., vol. 77, no. 5, pp. 873–882, 2002.
[13] [13] M. Esteves and A. Agarwal, “Impact of varicocele and its treatment on male fertility,” Arab J. Urol., vol. 9, no. 2, pp. 141–148, 2011.
[14] [14] J. I. Baazeem et al., “Varicocele and male factor infertility treatment: A new meta-analysis and review of the role of varicocelectomy,” Eur. Urol., vol. 60, no. 4, pp. 796–808, 2011.
[15] [15] R. Damsgaard, J. Joensen, N. Carlsen, A. Erenpreiss, and N. Jørgensen, “Varicocele is associated with impaired semen quality and reproductive hormone levels: A study of 7035 healthy young men from six European countries,” Eur. Urol., vol. 70, no. 6, pp. 1019–1029, 2016.

