Assessment of Some Heavy Metal Concentrations in Noodle Samples from Iraqi Markets and Study Probabilistic Health Risks Associated
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Using the acid digestion method and flame atomic absorption spectrometry, the current study examined the amounts of heavy metals, lead (Pb), cadmium (Cd), chromium (Cr), and nickel (Ni), in popular instant noodles used in Iraq (imported or local). In addition, a non-carcinogenic risk assessment was also conducted by determining a target hazard quotient (THQ) for the heavy metal ingestion risk to children and adults. The results showed a large range in heavy metal concentrations among the brands with lead the range of 0.94- 1.7 mg/kg, which is higher than the amount refered by the WHO of 0.5 mg/kg, cadmium in the range of 0.064 mg/kg to 0.13 mg/kg, higher than the recommended level by the World Health Organisation of 0.03 mg/kg, chromium in the range of 0.19- 0.41 mg/kg, higher than the recommended level by the WHO of 0.19 mg/kg, and nickel in the range of 0.008- 0.021mg/kg, greater than the 0.01 mg/kg WHO-recommended level. The Target Hazard Quotient (THQ), which is based on Monte Carlo simulations, was used to evaluate the health hazards. The results showed that all the elements' THQ values were below 1, meaning there was no immediate non-cancer threat to children and adults. Nickel and chromium were not found to have any effect, however, cadmium and lead were responsible for more than 99% of the total risk. Also, it was found that children were more susceptible to the negative effects than the adults. If cumulative health effects are possible with repeated exposures it means that continued monitoring programs of heavy metals in foods are needed and the quality of the raw materials and manufacturing process should be improved.
[1] C. Singh et al., “Nutrition role in maintaining health and preventing disease,” Current Nutrition & Food Science, vol. 20, no. 8, pp. 966–972, 2024.
[2] O. H. Adejuwon, A. I. O. Jideani, and K. O. Falade, “Quality and public health concerns of instant noodles as influenced by raw materials and processing technology,” Food Reviews International, vol. 36, no. 3, pp. 276–317, 2020.
[3] Y. Gao, X. Wang, and Y. Shi, “The types, regional distribution, and consumption trend of Chinese traditional wheat-based foods,” Journal of Food Quality, vol. 2022, Art. no. 9986119, 2022.
[4] J.-N. Liang et al., “Evaluation of wheat noodles supplemented with soy protein isolate for nutritional, textural, cooking attributes and glycemic index,” Applied Sciences, vol. 13, no. 13, Art. no. 7772, 2023.
[5] M. Rahimi et al., “Effect of substituting wheat flour with protein-rich sources on quality of instant noodles,” Journal of Food Processing and Preservation, vol. 2024, Art. no. 3431735, 2024.
[6] U. D. Le and B. Phayaphrom, “Factors influencing foreigners’ customer intention to purchase Vietnamese traditional instant noodles: The case of Ho Chi Minh City, Vietnam.”
[7] P. B. Angon et al., “Sources, effects and present perspectives of heavy metals contamination: Soil, plants and human food chain,” Heliyon, vol. 10, no. 7, 2024.
[8] A. Joseph et al., “Spice-induced metal contamination and microbiological risk assessment of instant noodles prepared for human consumption,” Biological Trace Element Research, vol. 202, no. 10, pp. 4787–4801, 2024.
[9] F. O. Ohiagu et al., “Human exposure to heavy metals: Toxicity mechanisms and health implications,” Material Science & Engineering International Journal, vol. 6, no. 2, pp. 78–87, 2022.
[10] A. C. Olufemi, A. Mji, and M. S. Mukhola, “Potential health risks of lead exposure from early life through later life: Implications for public health education,” International Journal of Environmental Research and Public Health, vol. 19, no. 23, Art. no. 16006, 2022.
[11] H. Maria et al., “The impact of lead (Pb) on health,” Journal of Global Research in Public Health, vol. 10, no. 1, pp. 1–14, 2025.
[12] A. E. Charkiewicz et al., “Cadmium toxicity and health effects—A brief summary,” Molecules, vol. 28, no. 18, Art. no. 6620, 2023.
[13] N. A. Suciu et al., “Cd content in phosphate fertilizer: Which potential risk for the environment and human health?,” Current Opinion in Environmental Science & Health, vol. 30, Art. no. 100392, 2022.
[14] K. Temelkovska et al., “Arsenic: Exposure through the food chain, toxicity, and toxicity reduction by nutritional compounds,” Journal of Food Technology & Nutrition, vol. 6, nos. 11–12, pp. 32–42, 2023.
[15] A. Hashim, “Human health effects of chronic arsenic exposure,” in Arsenic Toxicity Remediation: Biotechnological Approaches. Cham, Switzerland: Springer Nature Switzerland, 2023, pp. 45–60.
[16] G. Genchi et al., “Arsenic: A review on a great health issue worldwide,” Applied Sciences, vol. 12, no. 12, Art. no. 6184, 2022.
[17] D. C. Filipoiu et al., “Characterization of the toxicological impact of heavy metals on human health in conjunction with modern analytical methods,” Toxics, vol. 10, no. 12, Art. no. 716, 2022.
[18] M. Abtahi et al., “The concentration of BTEX in the air of Tehran: A systematic review-meta analysis and risk assessment,” International Journal of Environmental Research and Public Health, vol. 15, no. 9, Art. no. 1837, 2018.
[19] B. Ghasemidehkordi et al., “Concentration of lead and mercury in collected vegetables and herbs from Markazi province, Iran: A non-carcinogenic risk assessment,” Food and Chemical Toxicology, vol. 113, pp. 204–210, 2018.
[20] Y. Fakhri et al., “Systematic review and health risk assessment of arsenic and lead in the fished shrimps from the Persian Gulf,” Food and Chemical Toxicology, vol. 113, pp. 278–286, 2018.
[21] J. Rahmani et al., “A systematic review and meta-analysis of metal concentrations in canned tuna fish in Iran and human health risk assessment,” Food and Chemical Toxicology, vol. 118, pp. 753–765, 2018.
[22] M. Yousefi et al., “Polycyclic aromatic hydrocarbons (PAHs) content of edible vegetable oils in Iran: A risk assessment study,” Food and Chemical Toxicology, vol. 118, pp. 480–489, 2018.
[23] B. Tajdar-Oranj et al., “The concentration of heavy metals in noodle samples from Iran’s market: Probabilistic health risk assessment,” Environmental Science and Pollution Research, vol. 25, no. 31, pp. 30928–30937, 2018.
[24] V. Elumalai, K. Brindha, and E. Lakshmanan, “Human exposure risk assessment due to heavy metals in groundwater by pollution index and multivariate statistical methods: A case study from South Africa,” Water, vol. 9, no. 4, Art. no. 234, 2017.
[25] H. Keramati et al., “Radon-222 in drinking water resources of Iran: A systematic review, meta-analysis and probabilistic risk assessment (Monte Carlo simulation),” Food and Chemical Toxicology, vol. 115, pp. 460–469, 2018.
[26] A. Zafarzadeh et al., “Heavy metal (Pb, Cu, Zn, and Cd) concentrations in the water and muscle of common carp (Cyprinus carpio) fish and associated non-carcinogenic risk assessment: Alagol wetland in Golestan, Iran,” Toxin Reviews, vol. 37, no. 2, pp. 154–160, 2018.
[27] M. Abtahi et al., “Heavy metals (As, Cr, Pb, Cd and Ni) concentrations in rice (Oryza sativa) from Iran and associated risk assessment: A systematic review,” Toxin Reviews, vol. 36, no. 4, pp. 331–341, 2017.
[28] Y. Fakhri et al., “Health risk assessment induced by chloroform content of the drinking water in Iran: Systematic review,” Toxin Reviews, vol. 36, no. 4, pp. 342–351, 2017.
[29] M. Adel et al., “Heavy metal concentration in muscle of pike (Esox lucius Linnaeus, 1758) from Anzali International Wetland, southwest of the Caspian Sea and their consumption risk assessment,” Toxin Reviews, vol. 35, nos. 3–4, pp. 217–223, 2016.
[30] N. Razzaghi et al., “The concentration and probabilistic health risk assessment of pesticide residues in commercially available olive oils in Iran,” Food and Chemical Toxicology, vol. 120, pp. 32–40, 2018.
[31] C.-Y. Chang, H.-Y. Yu, J.-J. Chen, F.-B. Li, H.-H. Zhang, and C.-P. Liu, “Accumulation of heavy metals in leaf vegetables from agricultural soils and associated potential health risks in the Pearl River Delta, South China,” Environmental Monitoring and Assessment, vol. 186, no. 3, pp. 1547–1560, 2014.
[32] M. Ercilla-Montserrat et al., “A study on air quality and heavy metals content of urban food produced in a Mediterranean city (Barcelona),” Journal of Cleaner Production, vol. 195, pp. 385–395, 2018.
[33] S. Divanian, B. Akbari-Adergani, and P. Ziarati, “Study on chemical contamination problem in macaroni and pasta production technology,” Journal of Pharmaceutical & Health Sciences, vol. 4, no. 3, pp. 227–235, 2016.
[34] J. S. Jothi and M. B. Uddin, “Detection of heavy metals in some commercial brands of noodles,” European Academic Research, vol. 2, no. 8, pp. 10667–10679, 2014.
[35] H. Wu, J. Liang, and H. Han, “A novel method for the determination of Pb²⁺ based on the quenching of the fluorescence of CdTe quantum dots,” Microchimica Acta, vol. 161, no. 1, pp. 81–86, 2008.
[36] C. T. Onyema et al., “Quality assessment of common instant noodles sold in Nigeria markets,” American Journal of Analytical Chemistry, vol. 5, no. 17, pp. 1174–1187, 2014.
[37] I. A. Charles, A. J. Ogbolosingha, and I. U. Afia, “Health risk assessment of instant noodles commonly consumed in Port Harcourt, Nigeria,” Environmental Science and Pollution Research, vol. 25, no. 3, pp. 2580–2587, 2018.
[38] G. R. Jahed Khaniki et al., “Trace metal contaminants in Iranian flat breads,” Journal of Agriculture and Social Sciences, vol. 1, no. 4, pp. 301–303, 2005.
[39] Joint FAO/WHO Expert Committee on Food Additives and World Health Organization, Evaluation of Certain Contaminants in Food: Seventy-Second Report of the Joint FAO/WHO Expert Committee on Food Additives. Geneva, Switzerland: World Health Organization, 2011.
[40] G. M. A. Bermudez et al., “Heavy metal and trace element concentrations in wheat grains: Assessment of potential non-carcinogenic health hazard through their consumption,” Journal of Hazardous Materials, vol. 193, pp. 264–271, 2011.
[41] M. Pirhadi et al., “Heavy metals in wheat grain and its impact on human health: A mini-review,” Journal of Chemical Health Risks, vol. 12, no. 3, 2022.
[42] V.-T. Nguyen et al., “Analytical techniques for determination of heavy metal migration from different types of locally made plastic food packaging materials using ICP-MS,” Food Science & Nutrition, vol. 11, no. 7, pp. 4030–4037, 2023.
[43] Y. Tao et al., “Distribution and bioaccumulation of heavy metals in aquatic organisms of different trophic levels and potential health risk assessment from Taihu Lake, China,” Ecotoxicology and Environmental Safety, vol. 81, pp. 55–64, 2012.
[44] THAKUR, Ravindra Singh, et al. Evaluation of heavy metal contaminants in prepared noodles: source allocation and health risk assessment. Environmental Science and Pollution Research, 2023, 30.10: 25181-25192.
[45] P. Suwannaporn, K. Wiwattanawanich, and R. F. Tester, “Effect of water requirement and alkali on wheat–rice noodle quality,” Starch/Stärke, vol. 66, pp. 475–483, 2014.

