Gastrointestinal Motility and Postprandial Comfort with a Multi-Botanical Instant Granule: Experimental Evaluation and Human Product-Consumption Findings
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A staged NVTIA® botanical granule containing Poria cocos, coix seed, dandelion leaf, corn silk, citrus peel, cranberry, and fennel seed was examined for gastrointestinal motility and postprandial comfort. In the dampness-heavy-state mouse model, gastric emptying and small-intestinal propulsion were 42.1% and 45.7% in the model group and 56.8% and 61.3% after formulation 1; normal-group values were 63.5% and 68.4%. Adults with at least three prespecified bodily sensations consumed 4.0 g once daily for 14 days, 20 participants per group. With formulation 1, postprandial bloating changed from 6.4 to 3.1 and the five-domain total from 31.8 to 15.6, a 51.0% reduction. Direct mixing and selected ingredient-omission comparators produced smaller changes. Human studies of fennel-containing interventions and coix seed provide ingredient-level digestive context, while experimental and human work on Poria cocos, cranberry, and citrus helps define plausible intestinal and microbiome pathways. The results identify gastric emptying, intestinal propulsion, postprandial bloating, and bowel sensations as separate endpoints for subsequent controlled evaluation of the complete formulation.
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