Preparation and Diagnosis of a Nano-Pharmaceutical Compound Derived From Graphene Oxide
Downloads
In this research, a pharmaceutical nanocomposite derived from graphene oxide was prepared and characterized using the halbridiol drug. The first step involved synthesizing graphene oxide using the modified Hummers method. Next, the composite was created by reacting the graphene oxide with the halbridiol drug in deionized water as the solvent, utilizing sublimation. The validity of the prepared compound was confirmed through characterization using various spectroscopic methods, including FT-IR, FESEM, and XRD.
Hummers, W. S. Offeman, R. E. (1958). "Preparation of Graphitic Oxide". Journal of the American Chemical Society. 80 (6): 1339.
Sadri, R., Zangeneh Kamali, K., Hosseini, M., Zubir, N., Kazi, S. N., Ahmadi, G., & Golsheikh, A. M. (2017). Experimental study on thermo-physical and rheological properties of stable and green reduced graphene oxide nanofluids: Hydrothermal assisted technique. Journal of dispersion science and technology, 38(9), 1302-1310.
Feicht, P, Siegel, R, Thurn, H., Neubauer, J. W., Seuss, M., Szabó, T., ... & Breu, J. (2017). Systematic evaluation of different types of graphene oxide in respect to variations in their in-plane modulus. Carbon, 114, 700-705.
Marcano, D. C, Kosynkin, D. V., Berlin, J. M., Sinitskii, A., Sun, Z., Slesarev, A., ... & Tour, J. M. (2010). Improved synthesis of graphene oxide. ACS nano, 4(8), 4806-4814.
Loh, K., Bao, Q., Eda, G. & Chhowalla, M. Graphene oxide as a chemically tunable platform for optical applications. Nat. Chem. 2, 1015–1024 (2010).
Hegab, H. M. & Zou, L. Graphene oxide-assisted membranes: fabrication and potential applications in desalination and water purification. J. Membr. Sci. 484, 95–106 (2015).
Ma, M., Li, H., Xiong, Y. & Dong, F. Rational design, synthesis, and application of silica/graphene-based nanocomposite: a review. Mater. Des. 198, 109367 (2021).
Lee, E. G., Shin, K. Y., Lee, J. & Lee, S. S. Flexible free-standing composite films having 3D continuous structures of hollow graphene ellipsoids. Macromol. Res. 23, 552–558 (2015).
Wang, H., Maiyalagan, T. & Wang, X. Review on recent progress in nitrogen-doped graphene: synthesis, characterization and its potential applications. ACS Catal. 2, 781–794 (2012).
Choi, S., Kim, C., Suh, J. M. & Jang, H. W. Reduced graphene oxide-based materials for electrochemical energy conversion reactions. Carbon Energy 1, 85–108 (2019).
Robinson, J. T., Perkins, F. K., Snow, E. S., Wei, Z. & Sheehan, P. E. Reduced Graphene oxide molecular sensors. Nano Lett 8, 3137–3140 (2008).
Priyadarsini, S., Mohanty, S., Mukherjee, S., Basu, S. & Mishra, M. Graphene and graphene oxide as nanomaterials for medicine and biology applications. J. Nanostruct. Chem. 8, 123–137 (2018).
Otsuka, H., Urita, K., Honma, N., Kimuro, T., Amako, Y., Kukobat, R., ... & Kaneko, K. (2024). Transient chemical and structural changes in graphene oxide during ripening. Nature Communications, 15(1), 1708.
Rahman, S., & Marwaha, R. (2020). Haloperidol.
Mahmood, H. G. A., Al-Sumaida, G. H. A. W., & Hamdi, A. Q. Preparation and diagnosis of nanographene oxide and nanographene oxide derivatives. Journal of Education and Scientific Studies, 2(20). (2022).
Wibisono, Y., Fadila, C. R., Saiful, S., & Bilad, M. R. Facile approaches of polymeric face masks reuse and reinforcements for micro-aerosol droplets and viruses filtration: A review. Polymers, 12(11), 2516. (2020).

